Theirs is the school of hard truths. The understanding that healing can often hurt more than the damage felt at the start & recognizing that many cures feel a whole lot like poison are both wisdom from a serpent's point of view. We improve through duress and difficulty, becoming stronger and more viable as a direct response to whatever duress we feel and act upon.
When you feel like you're being forced to shed one skin and begin anew, that's an act of embracing serpent's wisdom. You're going through the very same destruction and renewal process that keeps them fresh and you'll find that it keeps you healthy and whole in return. When these things come up, lean into them, draw from the experiences and let them renew you. As much as they might suck, these are sacred things.
Have the experience, take the bitter pill and learn from it. The path of purpose has some resistance to it. ;)